Experimental COVID shot made via egg-based technology elicits a higher antibody proportion than mRNA vax
Neutralizing activity of vaccinee and convalescent serum samples against wild-type SARS-CoV-2 and Delta and Beta variants. Neutralization was measured against (A) wild-type SARS-CoV-2 strain USA-WA01/2020, (B) a Delta (B.1.617.2) isolate, and (C) a Beta (B.1.351) isolate in a microneutralization assay with authentic SARS-CoV-2. For vaccine groups, n = 35, nBNT162b2 = 20, and nHCS = 18. The exception is n3μg = 34 in (B) and n3μg = 31 in (C); n1 μg = 34 nd n3μg + ODN1018 = 34 in (C); and the nplacebo = 34 in (A) and nplacebo = 32 in (B) and (C), due to a lack of sample volume. Bars show GMT, and error bars indicate SD of the GMT. The horizontal dotted lines indicate the limit of detection; values below the limit of detection were assigned a value of half